PTH inactivates the AKT survival pathway in the colonic cell line Caco-2
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چکیده
منابع مشابه
Cytotoxic Activity of the Root of Euphorbia Tehranica Ethanolic Extract Against Caco-2 Colorectal Cancer Cell Line
Introduction: Efforts are made to identify the new potential components such as anticancer drugs. Medicinal plants belonging to Euphorbia genus are widely studied with promising effects. The current study aimed at investigating the effect of ethanolic extract of the root of E. tehranica, grown in Iran, on Caco-2 human colorectal cancer cell-line. Methods: The Caco-2 cells were treated with dif...
متن کاملChanges in the cellular behaviour of human colonic cell line Caco-2 in response to butyrate treatment.
Gut-derived adenocarcinoma Caco-2 cells were treated with sodium butyrate (NaB) at physiologically relevant concentrations. We characterized its effects on proliferation, differentiation, apoptosis, adhesion to the solid support and interleukin-8 secretion. Differentiation was determined by brush border alkaline phosphatase activity. Apoptosis was assessed by acridine orange and Hoechst stains....
متن کاملCytotoxic Activity of the Root of Euphorbia Tehranica Ethanolic Extract Against Caco-2 Colorectal Cancer Cell Line
Introduction: Efforts are made to identify the new potential components such as anticancer drugs. Medicinal plants belonging to Euphorbia genus are widely studied with promising effects. The current study aimed at investigating the effect of ethanolic extract of the root of E. tehranica, grown in Iran, on Caco-2 human colorectal cancer cell-line. Methods: The Caco-2 cells were treated with dif...
متن کاملEvaluation of Iron Bioavailability in Caco-2 cell Culture Model: Modification of the Original Method
Background and Objectives: In the original in vitro method for evaluation of iron bioavailability using caco-2 cell model, ferritin formation by cells is considered as a functional indicator of both absorption and utilization of iron. However, as iron is measured in the tested material and then ferritin concentration is measured in caco-2 cell lysate, it is almost impossible to have a concrete ...
متن کاملEvidence for two different broad - specific oligopeptide transporters in the 1 intestinal cell line Caco - 2 and the colonic cell line CCD 841
Evidence for two different broad-specific oligopeptide transporters in the 1 intestinal cell line Caco-2 and the colonic cell line CCD841 2 3 Paresh Chothe, Nagendra Singh and Vadivel Ganapathy 4 5 Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, GA 6 30912, U. S. A. 7 8 Address for reprint requests and other correspondence: V. Ganapathy, Department of 9 Bi...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 2010
ISSN: 0167-4889
DOI: 10.1016/j.bbamcr.2009.11.011